Across Barriers’ in-vitro ocular model, also called Human Cornea Construct HCC, contains immortalized human corneal epthelial cells (HCE-T) and corneal keratocyte cells (HCK-Ca).
With the help of the Across Barriers’ corneal model the following questions can be investigated:
- How can ophthalmic formulations be developed and optimized?
- How can the in-vitro permeability of test compounds be determined?
- How can the tolerance of the eye towards drugs and excipients be evaluated?