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Across Barriers’ in-vitro ocular model, also called Human Cornea Construct HCC, contains immortalized human corneal epthelial cells (HCE-T) and corneal keratocyte cells (HCK-Ca).

With the help of the Across Barriers’ corneal model the following questions can be investigated:

  • How can ophthalmic formulations be developed and optimized?
  • How can the in-vitro permeability of test compounds be determined?
  • How can the tolerance of the eye towards drugs and excipients be evaluated?

Factsheet "3 D-Cornea Model"